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Probiotics and Weight Management

Probiotics and Weight Management

ln 2006, Prof. Jeffrey Gordon and his group at Washington University in St. Louis reported in Nature ( Vol.444, pp. 1022-1023,1027-1031) that microbial populations in the gut are different between obese and lean people, and that when the obese people lost weight, their microflora reverted back to that observed in a lean person, suggesting that obesity may have a microbial component.

Dr Gordon and his group recently pushed back the scientitic boundaries even further in this area. In an elegant study, the St Louis-based scientists reported that probiotics in a yogurt did not colonize the gut microflora when studied in identical twins, but an additional study in mice revealed that ingestion of probiotic bacteria produced a change in many metabolic pathways, particularly those related to carbohydrate metabolism (Science translational Medicine, Vo.3,106ra106).

Source: The journal of Biological Chemistry "Beneficial metabolic effects of a probiotic via butyrate induced GLP-1 secretion’’ Authors: H. Yadav, J-H. Lee, J. LIoyd, P. Walter, S.G. Rane
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